Publications

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20December 13, 2024 · Science

A synthetic protein-level neural network in mammalian cells

19September 6, 2024 · Current Opinion in Biomedical Engineering

What can protein circuit design learn from DNA nanotechnology?

18March 10, 2023 · Trends in Biotechnology

Protein circuit design using de novo proteins

17July 12, 2022 · bioRxiv

A synthetic protein-level neural network in mammalian cells

16February 16, 2022 · GEN Biotechnology

Competitive displacement of De Novo Designed HeteroDimers can reversibly control protein–protein interactions and implement feedback in synthetic circuits

15January 25, 2022 · Nature Machine Intelligence

Interpreting neural networks for biological sequences by learning stochastic masks

14April 29, 2021 · Cell

Programmable protein circuit design

13September 8, 2020 · Nature Communications

Modulating mechanical stability of heterodimerization between engineered orthogonal helical domains

12April 3, 2020 · Science

De novo design of protein logic gates

11January 31, 2020 · Nature Protocols

Rapid online buffer exchange for screening of proteins, protein complexes and cell lysates by native mass spectrometry

10November 22, 2019 · Science

Creating the protein version of DNA base pairing

9July 24, 2019 · Nature

De novo design of bioactive protein switches

8May 22, 2019 · PLOS Pathogens

Functional expression and characterization of the envelope glycoprotein E1E2 heterodimer of hepatitis C virus

7May 17, 2019 · Science

De novo design of tunable, pH-driven conformational changes.

6May 3, 2019 · J. Am. Chem. Soc.

Self-assembling 2D arrays with de novo protein building blocks

5January 3, 2019 · Nature

Programmable design of orthogonal protein heterodimers

4March 2, 2018 · Science

Accurate computational design of multipass transmembrane proteins

3September 15, 2017 · Science

A cargo-sorting DNA robot

2May 6, 2016 · Science

De novo design of protein homo-oligomers with modular hydrogen-bond network-mediated specificity

1May 1, 2012 · PLOS One

A game-theoretic model of interactions between Hibiscus latent Singapore virus and tobacco mosaic virus